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Jain, Sunil K.: Lectin Conjugated Gastro-Retent...
49,00 € *
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Erscheinungsdatum: 08/2012, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Lectin Conjugated Gastro-Retentive Delivery System, Titelzusatz: Gastro-Retentive Multiparticulate Delivery System of Clarithromycin for the Effective Treatment of Helicobacter Pylori, Autor: Jain, Sunil K. // Jangdey, Manmohan Singh, Verlag: LAP Lambert Academic Publishing, Sprache: Englisch, Rubrik: Pharmazie // Pharmakologie, Toxikologie, Seiten: 80, Informationen: Paperback, Gewicht: 136 gr, Verkäufer: averdo

Anbieter: averdo
Stand: 06.12.2019
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Probiotics
136,99 € *
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Probiotic has been used for centuries especially in fermented dairy products since Metchnikoff associated the intake of fermented milk with prolonged life. Probiotics confer many health benefits to humans, animals, and plants when administered in proper amounts. These benefits include the prevention of gastrointestinal infections and antibiotic-associated diarrhea, the reduction of serum cholesterol and allergenic and atopic complaints, and the protection of the immune system. Furthermore, the proper usage of probiotics could suppress Helicobacter pylori infection and Crohn's disease, improve inflammatory bowel disease, and prevent cancer. In this book, we present specialists with experience in the field of probiotics exploring their current knowledge and their future prospects.

Anbieter: Thalia AT
Stand: 06.12.2019
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Proton Pump Inhibitors
175,99 € *
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This monograph contains a description of the discovery and development of a antisecretory therapy in the treatment of acid-related diseases: omeprazole, the first proton pump inhibitor. Overviews compare this and other proton pump inhibitors and discuss their pharmacology, including the mechanism of action, the effect on Helicobacter pylori infection, and the consequences of profound inhibition of gastric acid secretion. The pharmaceutic delivery system is described since it constitutes a special problem with this class of drugs. The clinical experience with proton pump inhibitors in acid-related diseases is reviewed with focus on gastro-esophageal reflux disease and peptic ulcer diseases including Helicobacter pylori and NSAID-induced ulcerations and Zollinger-Ellison syndrome. Finally, an overview is presented on the socio-economic impact of proton pump inhibitors in acid-related diseases emphasizing the important aspect of quality of life. The monograph is aimed at a broad readership with an interest in the development problems of this, at present, most commercially successful drug; the pharmacology of a 'tailor-made' drug for a specific target; the therapeutic strategies in acid-related diseases; and the dramatic changes in the long-term outcome results of the treatment of peptic ulcer diseases where most patients now can be cured from the disease after only one week of drug therapy.

Anbieter: Thalia AT
Stand: 06.12.2019
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Proton Pump Inhibitors
124,99 € *
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This monograph contains a description of the discovery and development of a antisecretory therapy in the treatment of acid-related diseases: omeprazole, the first proton pump inhibitor. Overviews compare this and other proton pump inhibitors and discuss their pharmacology, including the mechanism of action, the effect on Helicobacter pylori infection, and the consequences of profound inhibition of gastric acid secretion. The pharmaceutic delivery system is described since it constitutes a special problem with this class of drugs. The clinical experience with proton pump inhibitors in acid-related diseases is reviewed with focus on gastro-esophageal reflux disease and peptic ulcer diseases including Helicobacter pylori and NSAID-induced ulcerations and Zollinger-Ellison syndrome. Finally, an overview is presented on the socio-economic impact of proton pump inhibitors in acid-related diseases emphasizing the important aspect of quality of life. The monograph is aimed at a broad readership with an interest in the development problems of this, at present, most commercially successful drug; the pharmacology of a 'tailor-made' drug for a specific target; the therapeutic strategies in acid-related diseases; and the dramatic changes in the long-term outcome results of the treatment of peptic ulcer diseases where most patients now can be cured from the disease after only one week of drug therapy.

Anbieter: Thalia AT
Stand: 06.12.2019
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Sensor Technology for Water Quality Monitoring
175,99 € *
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Two methods for the detection of important human pathogens, Cryptosporidium parvum and Helicobacter pylori, were investigated: a fiber optic biosensor, and real time PCR. The mechanism for specific detection in both methods is recognition of specific DNA sequences in the target organisms. The biosensor that was used, the Analyte 2000, was originally developed for the detection of chemicals. It utilizes a fiber optic wave guide that propagates an evanescent light wave of very specific wavelength. The light excites fluorescent molecules bound to the waveguide, but not in the bulk solution, which theoretically enhances signal while reducing background interference. Attempts to develop this system for the detection of DNA were not successful due to poor detection of the target molecules. An assay analogous to a sandwich immunoassay was designed for use on the Analyte 2000. Specific oligonucleotide probes were designed to bind to the waveguides via biotin-streptavidin interaction, and were used to capture the target DNA. Pure target DNA representing unique genes in the organisms were synthesized by PCR. Detection of captured DNA was then attempted using an oligonucleotide detection probe designed to bind to the target. Two detection systems were employed: an indirect signal amplification system based on biotin-tyramide deposition, or direct detection of fluorescent signal from Cy-5 molecules. In all experiments performed there was very little difference between the signal generated with or without the target molecules. Many experiments were conducted to attempt to identify reasons for the poor signal. Signal was only of any significance when target amplicons were internally labeled with Cy-5 by PCR. Real time PCR as a method to detect the pathogens was also investigated. Though the PCR technique itself is very rapid, DNA extraction and purification requires preparation time. Filtration of up to one liter of well water, followed by concentration and 'cleaning' Helicobacter pylori cells by immunomagnetic separation, was used to detect H. pylori seeded in a water source. Following cell lysis, the extracted DNA could be used directly in conventional PCR targeting the 16S rRNA gene to detect less than 265 cells per liter of water. DNA purification was not required for this level of detection. Initial studies to amplify lysed cells by real time PCR indicated that an incorrect product was made. When purified DNA was used for real time PCR, the correct product was produced from DNA representing as few as 100 cells.

Anbieter: Thalia AT
Stand: 06.12.2019
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How Scientists Explain Disease
51,99 € *
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How do scientists develop new explanations of disease? How do those explanations become accepted as true? And how does medical diagnosis change when physicians are confronted with new scientific evidence? These are some of the questions that Paul Thagard pursues in this pathbreaking book that develops a new, integrative approach to the study of science. Ranging through the history of medicine, from the Hippocratic theory of humors to modern explanations of Mad Cow Disease and chronic fatigue syndrome, Thagard analyzes the development and acceptance of scientific ideas. At the heart of the book is a case study of the recent dramatic shift in medical understanding of peptic ulcers, most of which are now believed to be caused by infection by the bacterium Helicobacter pylori. When this explanation was first proposed in 1983, it was greeted with intense skepticism by most medical experts, but it became widely accepted over the next decade. Thagard discusses the psychological processes of discovery and acceptance, the physical processes involving instruments and experiments, and the social processes of collaboration, communication, and consensus that brought about this transformation in medical knowledge. How Scientists Explain Disease challenges both traditional philosophy of science, which has viewed science as largely a matter of logic, and contemporary science studies that view science as largely a matter of power. Drawing on theories of distributed computing and artificial intelligence, Paul Thagard develops new models that make sense of scientific change as a complex system of cognitive, social, and physical interactions. This is a book that will appeal to all readers with an interest in the development of science and medicine. It combines an engaging style, significant research, and a powerfully original argument.

Anbieter: Thalia AT
Stand: 06.12.2019
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Multiparticulate System For Peptic Ulcer
59,00 € *
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Multiparticulate System For Peptic Ulcer ab 59 EURO Novel Drug Delivery System For Helicobacter Pylori Induced Peptic Ulcer

Anbieter: ebook.de
Stand: 06.12.2019
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Lectin Conjugated Gastro-Retentive Delivery System
49,00 € *
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Lectin Conjugated Gastro-Retentive Delivery System ab 49 € als Taschenbuch: Gastro-Retentive Multiparticulate Delivery System of Clarithromycin for the Effective Treatment of Helicobacter Pylori. Aus dem Bereich: Bücher, Wissenschaft, Medizin,

Anbieter: hugendubel
Stand: 06.12.2019
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Lectin Conjugated Gastro-Retentive Delivery System
49,00 € *
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Lectin Conjugated Gastro-Retentive Delivery System ab 49 EURO Gastro-Retentive Multiparticulate Delivery System of Clarithromycin for the Effective Treatment of Helicobacter Pylori

Anbieter: ebook.de
Stand: 06.12.2019
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