Erscheinungsdatum: 21.11.2013, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Multiparticulate System For Peptic Ulcer, Titelzusatz: Novel Drug Delivery System For Helicobacter Pylori Induced Peptic Ulcer, Autor: Pandit, Vinay // Suresh, Sarasija, Verlag: LAP Lambert Academic Publishing, Sprache: Englisch, Rubrik: Pharmazie // Pharmakologie, Toxikologie, Seiten: 132, Informationen: Paperback, Gewicht: 213 gr, Verkäufer: averdo
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Prevalence of Helicobacter pylori (H. pylori) is very high and well documented in gastroenterological disorders like gastritis, gastric carcinoma, peptic ulcer disease, non ulcer dyspepsia and gastroesophageal reflux disease. More than 50% of the world's population harbor Helicobacter pylori in their upper gastrointestinal tract. It causes a chronic low-level inflammation of the stomach lining and is strongly linked to the development of duodenal and gastric ulcers and stomach cancer. This book will provide the readers a better understanding about the H. pylori related gastroenterological disorders and their proper management with clinical comparative research oriented herbal medicines.
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Medical scientists have found a new way to diagnose peptic ulcer by scrutinizing the colour, shape and coating of the human tongue. Indeed, medical experts have brought up evidence showing that this the analysis of the tongue should be done via acupuncture therapy. Therefore, in case of detection of the disease, peptic ulcer, the Chinese scientists have suggested to patients to get treatment from acupuncture treatment or herbal medicine therapy. Further research have shown that the tongue diagnosis techniques can also be used as a noninvasive auxiliary diagnostic method and as an indicator for clinical outcomes for patients with peptic ulcer disease. Medical scientists have explained that a human tongue which is invaded by the Helicobacter pylori infection and blood stasis within the tongue, indicates that the latter has already become a victim of stomach ulcer. The individuals who have received treatment acupunture therapy and herbal medicine therapy, usually possess a tongue with a healthy white color and sublingual vein engorgement. The multiple symptoms of peptic ulcer can be abdominal pain, internal bleeding, bloating, vomitting, melena, hematemesis...
Gastric ulcers are erupted when there is an disproportion between the digestive juices generated by the stomach and the diverse factors that defend the mucosal lining of the stomach. Acute gastric problem reduces quickly but Chronic gastric problems lead to ulcers. Nine out of ten Peptic ulcer disease(PUD) or peptic ulcer or stomach ulcer (Gastric and duodenal ulcers) are sore on the inner lining of stomach or deodenum and caused by an infection from the bacterium H. pylori and they are liable to reappear if left untreated. An ulcer in the stomach is called as a gastric ulcer, an ulcer in the duodenum is known as a duodenal ulcer, and a peptic ulcer of the esophagus is an esophageal ulcer. Peptic ulcer disease is suspect in patients with epigastic distress and pain. Peptic ulcers are usually caused by either Helicobacter pylori (H. pylori) bacteria or non-steroidal anti-inflammatory drugs such as Aspirin, Ibuprofen or other NSAIDs.
Peptic ulcer or Dyspepsia is one of the global`s diseases which causes mortality throughout the world, touching the lives of millions of peoples. For many years excess acid was believed to cause peptic ulcer. This misconception was suddenly illuminated due to the discovery of Helicobacter pylori bacteria which play a great role in the cause of peptic ulcer disease. To treat peptic ulcer natural products and modern synthetic drugs are in used but, still a complete cure has not been discovered and exploration of new antiulcer drugs has remain a field of active research. In this research a ground leaves of Tapinanthus dodoneifolius were macerated. The fractions obtained where subjected to phytochemicals screening, Antioxidant activity using DPPH and Antiulcer activity using an in vivo method on small animals. Causes, symptoms and treatment of peptic ulcer disease were discussed. The study has been a contribution to the assessment of possible antioxidant and antiulcer substances and should be useful to Biologist, Biochemists, Chemists, Health workers and other Medical practitioners.
Peptic ulcer disease (encompassing gastric ulcer and duodenal ulcer) disease affects a large portion of the world population. This occurs due to an imbalance between offensive and defensive factors. Helicobacter pylori infection is recognized as the leading cause of ulcer in the world, particularly in non developed countries, it comes under offensive factors and other agents such as alcohol and non steroidal anti-inflammatory drugs gain importance in developed countries comes under defensive factors. Nowadays the main line of approach in the treatment of peptic ulceration is the eradication of H. pylori infection. A large number of anti-ulcer drugs, including antibiotics, proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer disease, but clinical evaluations of these drugs have shown incidence of relapse, side effects, drug interactions and rebound hyper secretion following drug withdrawal which leads to high ulcer relapse rate. This has been the rationale for the development of new anti-ulcer drugs and thus search for novel molecules has been extended from plant sources that can offer better protection and have better safety profile.