Erscheinungsdatum: 07.01.2012, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Helicobacter pylori and Gastroduodenal Pathology, Auflage: Softcover reprint of the original 1st ed. 1993, Redaktion: Malfertheiner, Peter // Pajares, Jose M. // Pena, A. Salvador, Verlag: Springer Berlin Heidelberg // Springer Berlin, Sprache: Englisch, Schlagworte: Gastroenterologie // Hepatologie, Rubrik: Allgemeinmedizin // Diagnostik, Therapie, Seiten: 420, Informationen: Paperback, Gewicht: 633 gr, Verkäufer: averdo
Erscheinungsdatum: 22.09.2011, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Gastroduodenal Disease and Helicobacter pylori, Titelzusatz: Pathophysiology, Diagnosis and Treatment, Auflage: Softcover reprint of the original 1st ed. 1999, Redaktion: Czinn, Steven J. // Nedrud, John G. // Westblom, T. Ulf, Verlag: Springer Berlin Heidelberg // Springer Berlin, Sprache: Englisch, Schlagworte: Gastroenterologie // Mikrobiologie und Virologie // Pharmakologie, Rubrik: Allgemeinmedizin // Diagnostik, Therapie, Seiten: 332, Informationen: Paperback, Gewicht: 505 gr, Verkäufer: averdo
This book is a reflection of my thesis work submitted during my post graduation study. It highlights the association of Helicobacter pylori with various gastroduodenal diseases. Helicobacter pylori has been declared as a carcinogen by WHO and early detection of this organism in cases of dyspepsia not responding to conventional treatment, helps in preventing progression of such cases to malignancy. Early detection and treatment strategies will help in better management of patients.
Helicobacter pylori is one of the most common causes of chronic infections in human. A close relationship is now thought to exist between H. pylori and peptic ulcer disease, gastritis, and certain other gastroduodenal diseases. Also, it is now firmly established that infection with H. pylori is a key etiological factor in peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma. Furthermore, several studies have shown that eradication of H. pylori plays an important role in the treatment of some gastric-intestinal diseases. Biopsy specimens were collected from 150 dyspeptic patients. One hundred and seven were positive for H. pylori. Susceptibilities were determined for these isolates by disc diffusion methods. The prevalence of positive H. pylori isolates among the dyspeptic patients was 71.33%. The resistance rate to metronidazole, tetracycline, clarithromycin, and amoxicillin was 86%, 7.4%, 5.6%, and 0.9%, respectively. Metronidazole resistance was a character of H. pylori isolates within most patients in Ismailia, while amoxicillin resistance is rare.
In the rapidly evolving field of Helicobacter infection new data on pathogenetic and pathophysiological mechanism have appeared. New methods which will be more sensitive and specific in the diagnosis of the infection are being developed and in this proceedings the first attempt using PCR technology is published. From the clinical point of view, a challenging aspect that needs clarification, is the observation which suggests an appearance of a correlation between the presence of the bacteria and abdominal pain and other symptoms in children whereas in old age no such correlation is evident. The relationship of H. pylori and gastric cancer is studied with histopathological data and epidemiological approaches. On the treatment side schemes using short courses and new antibiotic combinations are being investigated and preliminary data are reported.