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Chronic Urticaria and Helicobacter pylori
45,90 € *
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The etiology of chronic spontaneous urticaria often remains un-established despite extensive investigative workup rendering cause specific management difficult. Foods, drugs, inhalants, systemic diseases, autoimmunity, and stress have been implicated frequently. Focal bacterial, viral and parasitic infections too have been involved in a significant number of cases and treating them empirically remains an unsubstantiated method in urticaria management. Helicobacter pylori infection has been also linked to chronic urticaria in 60-71% patients. Interestingly, H. pylori eradication treatment may lead to remission of urticaria in up to 80% patients including antihistamine unresponsive cases. The study notes a higher prevalence of asymptomatic H. pylori infection in a subset of chronic urticaria patients compared to controls. How it influences the chronicity, recurrences, severity or other manifestations of urticaria/angioedema, and its remission after eradication therapy remains conjectural in view of high endemicity of infection in developing countries in general.

Anbieter: Dodax
Stand: 03.12.2020
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Molecular Mechanisms of Inflammation: Induction...
140,54 € *
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This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world's population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection.This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori . Accordingly, it offers a valuable asset for scientists and clinicians alike.

Anbieter: Dodax
Stand: 03.12.2020
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Comprehensive Analysis on Acidity and Ulcers
45,90 € *
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Gastric ulcers are erupted when there is an disproportion between the digestive juices generated by the stomach and the diverse factors that defend the mucosal lining of the stomach. Acute gastric problem reduces quickly but Chronic gastric problems lead to ulcers. Nine out of ten Peptic ulcer disease(PUD) or peptic ulcer or stomach ulcer (Gastric and duodenal ulcers) are sore on the inner lining of stomach or deodenum and caused by an infection from the bacterium H. pylori and they are liable to reappear if left untreated. An ulcer in the stomach is called as a gastric ulcer, an ulcer in the duodenum is known as a duodenal ulcer, and a peptic ulcer of the esophagus is an esophageal ulcer. Peptic ulcer disease is suspect in patients with epigastic distress and pain. Peptic ulcers are usually caused by either Helicobacter pylori (H. pylori) bacteria or non-steroidal anti-inflammatory drugs such as Aspirin, Ibuprofen or other NSAIDs.

Anbieter: Dodax
Stand: 03.12.2020
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Helicobacter pylori Biomarkers for Diagnostic K...
49,90 € *
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Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world's population. H. pylori is also classified as class I carcinogen by the World Health Organization (WHO). There is a wide spectrum of clinical consequences by H. pylori, ranging from gastric cancer to ulceration of the gastrointestinal tract. The pathogenicity of the infection depends on the strain virulence, host susceptibility and environmental co-factors. During the process of H. pylori infection, the antigens secreted from the bacterium elicit strong humoral immune responses which may serve as prospective infection biomarkers. The infection has both direct and indirect impact on economic and overall well-being of patients, hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits and vaccines.

Anbieter: Dodax
Stand: 03.12.2020
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The Study of Association Between Helicobacter P...
39,90 € *
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This book is about the study of association between Helicobacter Pylori (H. pylori) and Chronic Obstructive Pulmonary Disease (COPD). In past years, many studies have been carried out to understand the complex relationship between H. pylori infection and COPD. Few researches have been successful in showing the epidemiologic and serologic evidence for relationship between these two phenomenon. In our study, we aimed to investigate the seroprevalence of Helicobacter pylori in patients with COPD and to determine whether there is an association between H. pylori infection and COPD. The results from our study suggest that there is higher prevalence of H. pylori seropositivity in COPD patients than in non-COPD patients and that HP infection has a positive correlation with the severity of COPD showing the prevalence of HP infection increases with the severeness of COPD. But we were not able to find out the reason for H. pylori infection being related to COPD since our study was carried out in a very small scale and short period of time. To understand the complex relationship between H. pylori infection and COPD, we look forward for a better technical support and a bigger study group.

Anbieter: Dodax
Stand: 03.12.2020
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Helicobacter pylori myths versus truth
49,00 € *
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Helicobacter pylori is one of the most common causes of chronic infections in human. A close relationship is now thought to exist between H. pylori and peptic ulcer disease, gastritis, and certain other gastroduodenal diseases. Also, it is now firmly established that infection with H. pylori is a key etiological factor in peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma. Furthermore, several studies have shown that eradication of H. pylori plays an important role in the treatment of some gastric-intestinal diseases. Biopsy specimens were collected from 150 dyspeptic patients. One hundred and seven were positive for H. pylori. Susceptibilities were determined for these isolates by disc diffusion methods. The prevalence of positive H. pylori isolates among the dyspeptic patients was 71.33%. The resistance rate to metronidazole, tetracycline, clarithromycin, and amoxicillin was 86%, 7.4%, 5.6%, and 0.9%, respectively. Metronidazole resistance was a character of H. pylori isolates within most patients in Ismailia, while amoxicillin resistance is rare.

Anbieter: Dodax
Stand: 03.12.2020
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Oral Floating In Situ Gel System For Furazolidone
61,90 € *
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Helicobacter pylori (H. Pylori) infection is associated with many upper gastrointestinal diseases such as chronic gastritis, peptic ulcer and gastric carcinoma. Furazolidone is an effective drug in the treatment of GIT infections. Furazolidone has short half-life and need to administrate on frequent basis. This book discuss design, development and optimization of sustained release intra-gastric in situ floating gel system of Furazolidone for the potential use in treatment of gastric and duodenal ulcers associated with H. Pylori. Furazolidone gelling solution (FISG) was prepared using natural biodegradable polymers Xanthan gum, Gellan gum and Locust bean gum. The polymeric system was optimized by calcium carbonate and sodium citrate. Effect of beta CD was also evaluated. The optimized FISG was evaluated for gelling properties, floating lag time, rheological properties, drug content, FT-IR and DSC. All optimized solutions had shown pseudoplastic flow with good gel strength and gelled immediately at acidic pH 1.2. The dissolution study indicated sustained release of drug. The book will be useful for the researchers working in the areas of formulation development of pharmaceuticals.

Anbieter: Dodax
Stand: 03.12.2020
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Bacterial flora in Crohn's disease tissues
79,00 € *
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Crohn s disease is an idiopathic, chronic, segmental and transmural inflammatory bowel disease. Three models implying a role for bacteria have been proposed: infection by a single, hitherto unknown pathogen, an unbalanced composition of the bowel flora, and an abnormally increased passage of bacteria through the bowel wall. We tested these hypotheses by an experimental approach combining morphology and molecular bacteriology. The test protocol consisted of microdissection of Crohn s lesions from histological slides, DNA isolation, purification and sequencing of bacterial DNA, and identification of bacteria based on these sequences. Legionellaceae were specific for Crohn. Ulcers in Crohn s disease were also enriched in Enterobacteriaceae. The bowel wall in Crohn s disease further contained larger numbers of bacteria than in controls. Overall, it is not yet possible to exclude the existence of a unique pathogen, such as in Helicobacter pylori-induced gastritis. Full-blown Crohn s disease is however clearly associated with important disturbances of the normal composition and spatial distribution of the intestinal flora.

Anbieter: Dodax
Stand: 03.12.2020
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Management of Helicobacter pylori infection
49,00 € *
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Prevalence of Helicobacter pylori (H. pylori) is very high and well documented in gastroenterological disorders like gastritis, gastric carcinoma, peptic ulcer disease, non ulcer dyspepsia and gastroesophageal reflux disease. More than 50% of the world's population harbor Helicobacter pylori in their upper gastrointestinal tract. It causes a chronic low-level inflammation of the stomach lining and is strongly linked to the development of duodenal and gastric ulcers and stomach cancer. This book will provide the readers a better understanding about the H. pylori related gastroenterological disorders and their proper management with clinical comparative research oriented herbal medicines.

Anbieter: Dodax
Stand: 03.12.2020
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